Tweetsie Railroad is located on Highway 321 between Boone and Blowing Rock, North Carolina. From the Blue Ridge Parkway exit at milepost 291 (Boone exit).
Note: US 321 through Blowing Rock may close for construction on Tuesdays and Thursdays from 11 am to 3 pm, and on Monday or Wednesday nights from 7 pm to
5 am. If closed, detour signs will be in place; be sure to allow for delays and/or detours. If traveling from Charlotte at these times, we recommend driving north on
I-77 to US 421, through Wilkesboro and Boone.